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INCREASE OF BONE MINERAL DENSITY BY CALCIUM SUPPLEMENT WITH OYSTER SHELL ELECTROLYSATE

INCREASE OF BONE MINERAL DENSITY BY CALCIUM SUPPLEMENT WITH OYSTER SHELL ELECTROLYSATE

Takuo Fujita 1, Masaaki Fukase 1, Haruko Miyamoto 2, Toshio Matsumoto 2 and Toru Ohue 2
1 Third Division, Department of Medicine, Kobe University School of Medicine, Kobe, Japan
2 Katsuragi Hospital, Kishiwada, Japan
Bone and Mineral (1990) 11: 85-91

Abstract
The effect of calcium supplementation, in patients with [bone loss] is still a matter of controversy. Oyster shell electrolysate (OSE) was reported to raise serum calcium and increase urinary calcium excretion in vitamin D-deficient states more readily than calcium carbonate. Since the effect of calcium salts on [bone loss] depends heavily on its bioavailability, the effect of 900 mg/day calcium as OSE was tested in 12 elderly females, using radial bone mineral density measured by single photon absorptiometry and spinal trabecular bone density measured by quantitative computed tomography (QCT) as indicated, in comparison with 21 untreated controls in the same geriatric hospital. Radial bone mineral density significantly increased from the pre-test value after 12 and 24 months in subjects given OSE by paired t-test, whereas it fell significantly in the controls. The spinal QCT value on OSE did not change significantly in either the subjects under treatment with OSE, or the controls. Thus OSE may favorably influence [bone loss] by providing a readily available source of calcium.

NOTE: "OSE" is AAACa (AdvaCAL) without HAI amino acid extract added.